| Date | Opponent | Time/TV | Tickets | |
| Tuesday Nov 1, 2022 |  | Western Oregon Wolves Exhibition McKale Center, Tucson, AZ | 7:30 PM MST PAC-12 Networks | Won 91-61 |
| Monday Nov 7, 2022 |  | Nicholls State Colonels McKale Center, Tucson, AZ | 7:30 PM MST PAC-12 Networks | Won 117-75 |
| Friday Nov 11, 2022 |  | Southern University Jaguars McKale Center, Tucson, AZ | 7:00 PM MST PAC-12 Networks | Won 95-78 |
| Thursday Nov 17, 2022 |  | Utah Tech Trailblazers McKale Center, Tucson, AZ | 7:00 PM MST PAC-12 Networks | Won 104-77 |
| Monday Nov 21, 2022 |  | Cincinnati Bearcats Maui Jim Maui Invitational Lahaina Civic Center, Lahaina, Hawaii | 9:30 PM MST ESPN2 | Won 101-93 |
| Tuesday Nov 22, 2022 |  | San Diego State Maui Jim Maui Invitational Lahaina Civic Center, Lahaina, Hawaii | 8:30 PM MST ESPN | Won 87-70 |
| Wednesday Nov 23, 2022 |  | Creighton Bluejays Lahaina Civic Center, Lahaina, Hawaii | 3:00 PM MST ESPN | Won 81-79 |
| Thursday Dec 1, 2022 |  | at Utah Utes Jon M. Huntsman Center, Salt Lake City, UT | 6:30 PM MST PAC-12 Networks | Lost 81-66 |
| Sunday Dec 4, 2022 |  | California Golden Bears McKale Center, Tucson, AZ | 3:00 PM MST PAC-12 Networks | Won 81-68 |
| Saturday Dec 10, 2022 |  | Indiana Hoosiers Las Vegas Clash MGM Grand Garden Arena, Las Vegas, NV | 5:30 PM MST FOX | Won 89-75 |
| Tuesday Dec 13, 2022 |  | Texas A&M Corpus Christi Islanders McKale Center, Tucson, AZ | 6:30 PM MST PAC-12 Networks | Won 99-61 |
| Saturday Dec 17, 2022 |  | Tennessee Volunteers McKale Center, Tucson, AZ | 8:30 PM MST ESPN2 | Won 75-70 |
| Tuesday Dec 20, 2022 |  | Montana State Bobcats McKale Center, Tucson, AZ | 6:30 PM MST PAC-12 Networks | Won 85-64 |
| Thursday Dec 22, 2022 |  | Morgan State Bears McKale Center, Tucson, AZ | 6:00 PM MST PAC-12 Networks | Won 93-68 |
| Saturday Dec 31, 2022 |  | at Arizona State Sun Devils Desert Financial Arena, Tempe, AZ | 12:00 PM MST FOX | Won 69-60 |
| Thursday Jan 5, 2023 |  | Washington Huskies McKale Center, Tucson, AZ | 9:00 PM MST FS1 | Won 70-67 |
| Saturday Jan 7, 2023 |  | Washington State Cougars McKale Center, Tucson, AZ | 3:00 PM MST PAC-12 Networks | Lost 74-61 |
| Thursday Jan 12, 2023 |  | at Oregon State Beavers Gill Coliseum, Corvallis, OR | 9:00 PM MST ESPN2 or ESPNU | Won 86-74 |
| Saturday Jan 14, 2023 |  | at Oregon Ducks Matthew Knight Arena, Eugene, OR | 4:00 PM MST ESPN2 | Lost 87-68 |
| Thursday Jan 19, 2023 |  | USC Trojans McKale Center, Tucson, AZ | 7:00 PM MST PAC-12 Networks | Won 81-66 |
| Saturday Jan 21, 2023 |  | UCLA Bruins McKale Center, Tucson, AZ | 12:00 PM MST ABC | Won 58-52 |
| Thursday Jan 26, 2023 | | at Washington State Cougars Beasley Coliseum, Pullman, WA | 9:00 PM MST FS1 | Won 63-58 |
| Saturday Jan 28, 2023 | | at Washington Huskies Alaska Airlines Arena at Hec Edmundson Pavilion, Seattle, WA | 3:30 PM MST FOX | Won 95-72 |
| Thursday Feb 2, 2023 | | Oregon Ducks McKale Center, Tucson, AZ | 8:30 PM MST ESPN | Won 91-76 |
| Saturday Feb 4, 2023 | | Oregon State Beavers McKale Center, Tucson, AZ | 7:30 PM MST PAC-12 Networks | Won 84-52 |
| Thursday Feb 9, 2023 | | at California Golden Bears Haas Pavilion, Berkeley, CA | 9:00 PM MST PAC-12 Networks | Won 85-62 |
| Saturday Feb 11, 2023 |  | at Stanford Cardinal Maples Pavilion, Stanford, CA | 6:00 PM MST ESPN2 | Lost 88-79 |
| Thursday Feb 16, 2023 | | Utah Utes McKale Center, Tucson, AZ | 8:00 PM MST PAC-12 Networks | Won 88-62 |
| Saturday Feb 18, 2023 |  | Colorado Buffaloes McKale Center, Tucson, AZ | 6:00 PM MST ESPN2 | Won 78-68 |
| Saturday Feb 25, 2023 | | Arizona State Sun Devils McKale Center, Tucson, AZ | 12:00 PM MST CBS | Lost 89-88 |
| Thursday Mar 2, 2023 | | at USC Trojans Galen Center, Los Angeles, CA | 9:00 PM MST ESPN | Won 87-81 |
| Saturday Mar 4, 2023 | | at UCLA Bruins Pauley Pavilion, Los Angeles, CA | 8:00 PM MST ESPN | Lost 82-73 |
| Thursday Mar 9, 2023 | | Stanford Cardinal Pac-12 Tournament – Quarterfinals T-Mobile Arena in Las Vegas, NV | 7:00 PM MST PAC-12 Networks | Won 95-84 |
| Friday Mar 10, 2023 | | Arizona State Sun Devils Pac-12 Tournament – Semifinals T-Mobile Arena in Las Vegas, NV | 9:30 PM MST ESPN | Won 78-59 |
| Saturday Mar 11, 2023 | | UCLA Bruins Pac-12 Tournament – Championship T-Mobile Arena in Las Vegas, NV | ESPN 8:30 PM MST | Won 61-59 |
| Thusday Mar 16, 2023 |  | Princeton Tigers NCAA Tournament Golden 1 Center, Sacramento, CA | TNT 1:10 PM MST | Lost 59-55 |
