| Date | Opponent | Time/TV | Tickets | |
| Fri Nov 27, 2020 |  | Grambling State Tigers McKale Center, Tucson, AZ | 3:00 PM MST PAC-12 Network | Won 74-55 |
| Sat Dec 5, 2020 |  | Eastern Washington Eagles McKale Center, Tucson, AZ | 12:00 PM MST PAC-12 Network | Won 70-67 |
| Mon Dec 7, 2020 |  | Northern Arizona Lumberjacks McKale Center, Tucson, AZ | 7:00 PM MST PAC-12 Network | Won 96-53 |
| Wed Dec 9, 2020 |  | CSU Bakersfield Roadrunners McKale Center, Tucson, AZ | 5:00 PM MST PAC-12 Network | Won 85-60 |
| Sat Dec 12, 2020 |  | UTEP Miners McKale Center, Tucson, AZ | 4:00 PM MST PAC-12 Network | Won 69-61 |
| Wed Dec 16, 2020 |  | California Baptist Lancers McKale Center, Tucson, AZ | 5:00 PM MST PAC-12 Network | Cancelled |
| Sat Dec 19, 2020 |  | at Stanford Cardinal Maples Pavilion, Stanford, CA | Time: TBA PAC-12 Network | Lost 78-75 |
| Tue Dec 22, 2020 |  | Montana Grizzlies McKale Center, Tucson, AZ | 5:00 PM MST PAC-12 Network | Won 70-64 |
| Mon Dec 28, 2020 |  | Colorado Buffaloes McKale Center, Tucson, AZ | 7:30 PM MST PAC-12 Network | Won 88-74 |
| Thu Dec 31, 2020 |  | at Washington Hec Edmundson Pavilion, Seattle, WA | 6:00 PM MST PAC-12 Network | Won 80-53 |
| Sat Jan 2, 2021 |  | at Washington State Beasley Coliseum, Pullman,WA | 8:30 PM MST PAC-12 Network | Won 86-82 2OT |
| Thu Jan 7, 2021 |  | USC McKale Center, Tucson, AZ | 7:00 PM MST ESPN2 | Lost 87-73 |
| Sat Jan 9, 2021 |  | UCLA McKale Center, Tucson, AZ | 7:00 PM MST ESPN | Lost 81-76 |
| Thu Jan 14, 2021 |  | at Oregon State Gill Coliseum, Corvallis, OR | 9:00 PM MST FS1 | Won 98-64 |
| Sat Jan 16, 2021 |  | at Oregon Matthew Knight Arena, Eugene, OR | 8:00 PM MST ESPN | Postponed |
| Thu Jan 21, 2021 |  | at Arizona State Desert Financial Arena, Tempe, AZ | 7:00 PM MST ESPN | Won 84-82 |
| Mon Jan 25, 2021 | | Arizona State McKale Center, Tucson, AZ | 9:00 PM MST ESPN2 | Won 80-67 |
| Thu Jan 28, 2021 | | Stanford McKale Center, Tucson, AZ | 8:00 PM MST ESPN2 | Lost 73-64 |
| Sat Jan 30, 2021 |  | California McKale Center, Tucson, AZ | 3:00 PM MST PAC-12 NETWORK | Won 71-50 |
| Thu Feb 4, 2021 |  | at Utah Jon M. Huntsman Center, Salt Lake City, UT | 5:00 PM MST FS1 | Lost 73-58 |
| Sat Feb 6, 2021 | | at Colorado CU Events Center, Boulder, CO | 6:00 PM MST FS1 | Lost 82-79 |
| Thu Feb 11, 2021 | | Oregon State McKale Center, Tucson, AZ | 6:00 PM MST PAC-12 Network | Won 70-61 |
| Sat Feb 13, 2021 | | Oregon McKale Center, Tucson, AZ | 12:00 PM MST ESPN2 | Lost 63-61 |
| Thu Feb 18, 2021 | | at UCLA Pauley Pavilion, Los Angeles, CA | 7:00 PM MST ESPN | Lost 74-60 |
| Sat Feb 20, 2021 | | at USC Galen Center, Los Angeles, CA | 4:00 PM MST FOX | Won 81-72 |
| Thu Feb 25, 2021 | | Washington State McKale Center, Tucson, AZ | 9:00 PM MST FS1 | Won 69-53 |
| Sat Feb 27, 2021 | | Washington McKale Center, Tucson, AZ | 12:00 PM MST CBS | Won 75-74 |
| Mon Mar 1, 2021 | | at Oregon Matthew Knight Arena, Eugene, OR | 7:00 PM MST ESPN2 | Lost 80-69 |
